AlphaFold Server
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Alphafold Server
Overview :
AlphaFold Server is an online service based on the AlphaFold3 model that can generate high-precision predictions of the structures of proteins, DNA, RNA, ligands, ions, etc., and can simulate chemical modifications of proteins and nucleic acids. Developed in collaboration between Google DeepMind and Isomorphic Labs, it is of great significance in the fields of scientific research and biopharmaceuticals. Particularly in non-commercial uses, it provides a powerful tool for predicting and analyzing biomolecular structures.
Target Users :
["Biomedical Researchers: Can use AlphaFold Server for protein and other biomolecule structure predictions, speeding up scientific research.","Drug Developers: Predicting molecular structures aids in drug design and target identification.","Bioinformatics Experts: Utilize the platform for complex biomolecular analysis and simulation."]
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Use Cases
Researchers use AlphaFold Server to predict the structure of a protein related to a disease to understand its function.
Drug companies use the platform to simulate drug-ligand interaction patterns to optimize drug design.
Educational institutions use AlphaFold Server as a teaching tool to help students understand the three-dimensional structures of biomolecules.
Features
Supports modeling of multiple biomolecule types, including proteins, DNA, RNA, etc.
Predicts the structures of ligands and ions.
Simulates common post-translational biomolecular modifications.
Provides confidence metrics for structure predictions, such as pLDDT and PAE.
Users can run up to 10 jobs per day.
Supports importing and exporting jobs through JSON files.
Provides detailed prediction results, including structure images and download options.
How to Use
Step 1: Visit the AlphaFold Server website and register an account.
Step 2: Select the type of biomolecule to predict, such as protein, DNA, or RNA.
Step 3: Enter the sequence information of the biomolecule or upload a FASTA file.
Step 4: Select possible ligands, ions, or post-translational modifications.
Step 5: Submit the job and wait for the prediction results.
Step 6: Review the confidence metrics of the structure prediction to evaluate the accuracy of the predictions.
Step 7: Download the prediction results, including structure images and JSON files.
Step 8: Analyze or use the prediction results further as needed.
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