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Alphaproteo
Overview :
AlphaProteo is the first AI system launched by DeepMind designed to create novel, high-affinity protein complexes as building blocks for biological and health research. This technology has the potential to accelerate our understanding of biological processes and support drug discovery and biosensor development. AlphaProteo can generate new protein complexes for a variety of target proteins, including VEGF-A, which is associated with cancer and diabetes complications. It outperforms existing methods in terms of experimental success rates and binding affinity, significantly reducing the time needed for preliminary experiments involving protein complexes.
Target Users :
AlphaProteo's target audience primarily includes biomedical researchers, drug development scientists, and biotechnology companies. These users can rapidly design and test novel proteins using AlphaProteo, accelerating research processes and enhancing experimental efficiency, leading to breakthroughs in areas such as disease treatment and biosensor development.
Use Cases
AlphaProteo successfully designed protein complexes targeting VEGF-A, contributing to research on cancer and diabetes.
In experiments at the Francis Crick Institute, a SC2RBD complex designed by AlphaProteo was able to block SARS-CoV-2 from infecting cells.
Collaborated with Isomorphic Labs to explore AlphaProteo's applications in drug design.
Features
Design novel protein complexes for biological and health research.
Generate high-affinity protein complexes targeting specific molecules.
Demonstrate higher success rates and binding affinity in experiments compared to existing methods.
Design complexes targeting key proteins like VEGF-A, aiding in disease understanding and treatment.
Optimize the protein design process by leveraging machine learning on extensive protein data.
Collaborate with research teams to validate the functionality and efficacy of the protein complexes.
Work with external experts on biosafety and ethical considerations to ensure responsibly developed technology.
How to Use
Visit the official AlphaProteo website or contact DeepMind for trial access.
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Provide structural information of the target molecule and preferred binding sites.
Utilize AlphaProteo's AI system to generate candidate protein complexes.
Test the generated protein complexes in a laboratory setting to verify their binding affinity.
Optimize and adjust the protein complexes based on experimental results.
Collaborate with research teams to explore the biological functions and potential applications of the protein complexes.
Stay updated with DeepMind's latest research progress and product updates to leverage cutting-edge technological advancements.
